The genetic polymorphisms in vitamin D receptor and the risk of type 2 diabetes mellitus: an updated meta-analysis.

Genetic Polymorphisms of Estrogen Receptors in Iranian Women with Diabetes and Coronary Artery Disease

Estrogen might play an important role in the pathogenesis of diabetes mellitus type 2. Estrogens inhibit diabetes via distinct mechanisms particularly by reducing both hyperglycemia and plasma insulin levels. Estrogen exerts its physiological effects mainly through estrogen receptors including α and β types. Estrogen receptors are found in many tissues that participate in the pathogenesis of ty...

بررسی ارتباط پلی مورفیسم‌های‌ شایع ژن گیرنده ویتامین D با خطر ابتلا به بیماری عروق کرونر قلب: شواهد حاصل از یک مطالعه متاآنالیز با 5259 مورد بیمار

Background:Previous studies evaluating the association between ApaI, FokI, TaqI, and BsmI polymorphisms of vitamin D receptor gene (VDR) and risk of coronary artery disease (CAD) have produced inconsistent results. The present meta-analysis of eligible studies was conducted to reveal whether this polymorphism plays a role in susceptibility to CAD. Methods: Literature search...

Evaluation of the relationship between different polymorphisms of vitamin D receptor gene and renal diseases in patients with type 2 diabetes in Khuzestan province

Meta-analysis of vitamin D receptor polymorphisms and type 1 diabetes: a HuGE review of genetic association studies.

Several polymorphisms in the vitamin D receptor (VDR) gene have been reported to be associated with the risk of developing type 1 diabetes, yet published findings have been conflicting. In this study, the authors attempted to evaluate the evidence regarding the association. They searched all relevant reports from original papers published from 1997 to December 2005. Predefined criteria were use...

Genetic polymorphisms of glutathione-s-transferase M1 and T1 genes with risk of diabetic retinopathy in Iranian population

Objective(s):To the best of our knowledge, this is the first report on the contributions of GST genetic variants to the risk of diabetic retinopathy in an Iranian population. Therefore, the objective of this study was to determine whether sequence variation in glutathione S-transferase gene (GSTM1 and GSTT1) is associated with development of diabetic retinopathy in type 2 diabetes mellitus (T2D...